LPD (lateralized periodic discharges)

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Synonyme: PLED (Periodic lateralized epileptiform discharges)

  • Lateralized: so unilateral
  • Periodic: Relative constant interval between the discharges, which varies between 0.5 and 3 seconds (most often around 1 second)
  • Discharge: Could be a Delta waves or sharp waves with a “epileptiform” morphology


  • LPD’s are seen in acute cerebral laesion
    • Non specific:
      • Acute cerebrovascular events
      • Encephalitis
      • Subdural hematoma
      • Other structural lesions
  • Tend to disappear in weeks
  • Higher risk of seizures in patients with LPD’s



LPD's left parieto occipital in a male of 78 years old with a hemmorrhage left occipital (average) LPD's left parieto occipital male 78 yo with a hemmorrhage left occipital (average).png