Difference between revisions of "CSWS (Continuous spike and wave during slow wave sleep)"

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==Background==  
 
==Background==  

Revision as of 10:30, 12 July 2017

CSWS (Continuous Spike and Wave during Sleep) syndrome and Landau Kleffner Syndrome (LKS)

Background

  • 1% of all epilepsy in childhood
  • Clinical onset usually 4-5 years old.
  • Usually- but not always- due to structural brain damage.
  • Landau Kleffner Syndrome (Acquired Epileptic Aphasia (AEA)) is a subtype of CSWS, with progressively loss of receptive and expressive language ability.

Clinics

  • Deterioration in development
  • Different types of seizures can be seen (sometimes after typical Rolandic epilepsy).
  • Dyspraxia
  • Speach disturbances (in fluency, understanding): When this symptom is prominent, LKS diagnosis is more likely.
  • Behavioural problems and memory disturances: When this symptom is prominent, CSWS syndrome (or nocturnal frontal lobe epilepsy, NFLS) is more likely.

EEG

  • Main feature is ESES (Electrical Status Epilepticus of Sleep) : synchronic discharges during NON REM sleep
  • Discharges are seen in 70-80% of the time during NON REM sleep




Author: Bas Jongbloed, MD, neurology resident, ETZ Tilburg, The Netherlands