SIRPID (Stimulus Induced Rhythmic, Periodic, or Ictal Discharges)

Background

• Stimulus Induced Rhythmic, Periodic, or Ictal Discharges (SIRPID)
• Due to cortical and subcortical brain damage (thalamo-cortical dysfunction)
• Often seen after acute brain injury (around 75%)
• Discharges are induced by a tactile stimulus, i.e. touch or pain.

Clinic

• In critically ill patients
• 50% has (sub)clinical seizures.
• Risk factor for development of status epilepticus.

EEG

• Encephalopatic background EEG
• Rhythmic delta discharges after a stimulus, i.e. pain.
• Generalized or focal discharges.
• Lasting seconds to hours

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Generalized SIRPIDs after pain stimulus (blue line) (Average)

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