Photoparoxysmal response

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  • Epileptiform discharges provoked by intermittent photic stimulation (flickering light)
  • Classfied in four types of photoparoxysmal response according to Waltz[1]:
    • Waltz 1: Spikes within the occipital rhythm
    • Waltz 2: Parieto-occipital spikes with a biphasic slow wave
    • Waltz 3: Parieto-occipital spikes with a biphasic slow wave and spread to the frontal region
    • Waltz 4: Generalized spikes and wave or polyspikes and wave


Clinical relevance

  • Photoparoxysmal responses are frequently found in nonepileptic children.
  • The prevalence of photosensitivity in nonepileptic individuals ranges from 0.5 to 8.9% of the population and rarely evolve into epilepsy
  • Only generalized paroxysmal epileptiform discharges (Waltz 4) are clearly linked to epilepsy.
  • The majority of individuals with photosensitive seizures does not need anticonvulsant therapy
  • Most effective treatment is avoidance of provoking stimulus.
  • Photosensitive epilepsy is also linked to headache.

Notes

  1. Waltz S, Christen H-J, Doose H: The different patterns of the photoparoxysmal response a genetic study. Electroencephalogr Clin Neurophysiol 1992;83:138-145