LPD (lateralized periodic discharges)

Synonyme: PLED (Periodic lateralized epileptiform discharges)

• Lateralized: Unilateral
• Periodic: Relative constant interval between the discharges, which varies between 0.5 and 3 seconds (most often around 1 second)
• Discharge: Could be Delta waves or sharp waves with a “epileptiform” morphology
• If a more ictal appearance it can be categorized as LPD+:
  • +F: superimposed fast activity.
  • +R: superimposed rhythmic or quasi-rhythmic activity.
  • +FR: superimposed fast activity and rhythmic or quasi-rhythmic activity.

• LPD’s are seen in acute cerebral laesion
  • Non specific:
    • Acute cerebrovascular events
    • Encephalitis
    • Subdural hematoma
    • Other structural lesions
• Tend to disappear in weeks
• Higher risk of seizures (50-80%) in patients with LPD’s

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LPD's left parieto occipital in a male of 78 years old with a hemmorrhage left occipital (average)

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Notes